<p>Cleanance Comedomed, an innovation from Laboratoires Eau Thermale Avène has shown proven clinical effectiveness from seven days*, fights spots from the root and prevents them from reappearing. Expert care for oily, acne-prone skin, Cleanance Comedomed is formulated using Comedoclastin, a plant extract from the seeds of milk thistle. This active ingredient with patented properties** directly targets microcomedones, reduces existing spots and blackheads, limits new ones appearing, and regulates the hyperproduction of sebum. Cleanance Comedomed is suitable for adults and teenagers from the age of 12, applied twice a day, morning and evening, and offers clinically-proven*** anti-recurrence action. Non-comedogenic, high-tolerance* for acne-prone skin, its fast-absorbing, non-greasy texture leaves skin mattified.<br> <br> *Tolerance and efficacy study under dermatological control on 51 subjects, use of Cleanance Comedomed twice a day for 56 days.<br> <br> ** Patent registered<br> <br> ***International clinical observational study, 90% of patients without acne relapse at T6 months, (according to the definition of relapse in the GEA protocol ≥3 requiring the introduction of a drug treatment – oral or local), 48 subjects, two applications per day of Cleanance Comedomed for six months.</p> <p>Targets acne, blackheads &amp; prevents recurrence ( For oily / acne-prone skin )</p> <p>Avene Thermal Spring Water (Avene Aqua), Isopropyl Alcohol, Peg-6. Glycerin, Silybum Marianum Fruit Extract, Silica, Polyacrylate-13, Polyisobutene, Polysorbate 20, Sorbitan Isostearate, Water (Aqua)</p> <p>France</p>